We don’t have real data on either the healthy or unhealthy side effects from cleansing methods," Wolf said. Most of the known side effects come from case reports described in the medical literature and not from research studies, of which there are few.
Colon cleansing with laxatives, herbal formulations or enemas might increase a person’s risk of becoming dehydrated if the individual does not drink enough fluids, Wolf said.
Inducing diarrhea can also change people’s electrolyte levels. Shifting levels of sodium might cause lightheadedness, and low potassium levels may cause leg cramps or abnormal heart rhythms, Wolf said.
Some herbal cleanses have also been linked with liver toxicity and aplastic anemia, a rare blood disorder.
Case reports suggest colon hydrotherapy may cause abdominal cramping, stomach pain, diarrhea, nausea and vomiting. More-severe complications may include perforating the bowel, serious infections, electrolyte imbalances, kidney problems and heart failure.