Does EDTA chelation work?

It’s unclear whether chelation therapy can treat heart disease. Chelation therapy has been used for many years as a treatment for mercury and lead poisoning, but it isn’t a proven treatment for heart disease. It can potentially cause serious side effects when used as a heart disease treatment. Even so, some doctors and complementary health practitioners have used chelation therapy to treat heart disease and stroke.

In chelation therapy, a dose of a medication called ethylenediaminetetraacetic acid (EDTA) is delivered into your bloodstream through an intravenous (IV) line. This medication seeks out and binds to minerals in your bloodstream. Once the medication binds to the minerals, it creates a compound that leaves your body in your urine.

The theory behind using chelation therapy for heart disease is that the medicine used in the treatment binds to the calcium that’s in fatty deposits (plaques) in your arteries. Once the medicine binds to the calcium, the plaques are swept away as the medicine moves through your bloodstream.

The safety and effectiveness of chelation therapy for heart disease can’t be determined, even after a large-scale study was conducted to determine just that. Results of the Trial to Assess Chelation Therapy (TACT), sponsored by the National Institutes of Health, didn’t provide enough evidence to support routine use of chelation therapy for heart disease.

The American Heart Association and the American College of Cardiology have determined that it’s uncertain whether chelation therapy is useful as a treatment for heart disease, and the Food and Drug Administration hasn’t approved chelation therapy for use as a heart disease treatment.

Some doctors are concerned about the safety of chelation therapy as a treatment for heart disease. A burning sensation at the IV site is the most common side effect. Less common side effects include fever, headache, nausea or vomiting. Other rare but serious complications that have been reported include abnormally low blood-calcium levels (hypocalcemia), permanent kidney damage or death.

Because of the known risks of chelation therapy, discuss this and other options with your doctor before trying chelation therapy as a heart disease treatment.