side effects of amitriptyline for migraine prevention

The downside is that amitriptyline does cause some side effects that sometimes cause people to discontinue it. These may include: dry mouth, fatigue, somnolence, weight gain, dizziness, constipation, sinusitis, and orthostatic hypotension — a drop in blood pressure when a person moves from a laying or sitting position to a standing position.

Amitriptyline may also increase a person’s risk of bone fractures, and cause a decrease in the number of blood cells, although this is rare.

Amitriptyline can also interact with a number of medications — so be sure to inform your doctor of all medications, over-the-counter supplements, and vitamins.