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statin side effects and drug interactions

Applies to simvastatin: oral suspension, oral tablet, oral tablet disintegrating

Along with its needed effects, simvastatin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking simvastatin:

More common
Dizziness
fainting
fast or irregular heartbeat
Less common
Bladder pain
bloody or cloudy urine
blurred vision
body aches or pain
chills
cough
dark-colored urine
difficult, burning, or painful urination
difficulty with breathing
difficulty with moving
dry mouth
ear congestion
fever
flushed, dry skin
frequent urge to urinate
fruit-like breath odor
headache
increased hunger
increased thirst
increased urination
joint pain
loss of consciousness
lower back or side pain
muscle cramps, spasms, or stiffness
muscular pain, tenderness, wasting, or weakness
nasal congestion
nausea
runny nose
sneezing
sore throat
stomachache
sweating
swelling
swollen joints
troubled breathing
unexplained weight loss
unusual tiredness or weakness
vomiting

A total of 280 drugs (802 brand and generic names) are known to interact with simvastatin.

80 major drug interactions (243 brand and generic names)
188 moderate drug interactions (506 brand and generic names)