Lorenzo’s Oil is a combination of a 4:1 mix of oleic acid and erucic acid, extracted from rapeseed oil and olive oil designed to normalize the accumulation of the very long chain fatty acids in the brain thereby slowing the progression of adrenoleukodystrophy (ALD). It is specific to ALD and is NOT designed to be used to treat other leukodystrophies nor Multiple Sclerosis.
In the United States, initial start and consent to use the oil needs to go through either Dr. Gerald Raymond or Dr. Ali Fatemi (see contact information below). Some medical insurance companies may provide coverage for the oil, but others do not because it is still considered to be an experimental drug by the Food and Drug Administration (FDA).
The oil, if started early in boys with adrenoleukodystrophy (ALD) showing no symptoms, is now known to have some benefit in preventing the childhood cerebral form of adrenoleukodystrophy. Researchers are still trying to understand the complex relationships among fats in the body, and how Lorenzo’s oil could be further modified to be more effective. The oil is designed to normalize the accumulation of the very long chain fatty acids in the brain that thereby halting the progression of ALD.
Lorenzo’s Oil is specific to ALD, does not repair myelin, and does not have any known effect on other demyelinating disorders, such as Multiple Sclerosis. In ALD pre-symptomatic boys, however, Lorenzo’s Oil can (but not always) slow down the onset of the disease by stopping the body from producing the very long chain fatty acids, whose buildup leads to demyelination. It is jointly manufactured by Croda International and The Scientific Hospital Supply, and it is distributed by Nutricia Advanced Medical Nutrition. To read an article published by pediatric neurologist Dr. Gerald Raymond about Lorenzo’s Oil and its effect on ALD, click here. For information about preparation and administration